Reversible Cardiomyopathy Associated with Cocaine Intoxication

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Abstract
Cocaine intoxication typically produces a profoundly enhanced sympathomimetic state and has been temporally associated with various serious, including fatal, medical disorders. Chief among these disorders are cardiovascular complications, principally acute myocardial infarction (1). Dilated cardiomyopathy has been reported only rarely in association with cocaine abuse (2, 3). We describe a patient who developed an acutely dilated cardiomyopathy temporally related to smoking ("free-basing") the "crack" formulation of cocaine. Over 2 weeks, however, serial noninvasive studies showed reversal of her cardiomyopathy with a marked improvement in left ventricular systolic function. This patient's course was similar to that of patients with reversible catecholamine

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