Zur Biochemie der Oxalsäure
- 1 January 1956
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 304 (Jahresband) , 173-181
- https://doi.org/10.1515/bchm2.1956.304.1-2.173
Abstract
1,2 C14-Oxalic acid was injected into rats to study its behavior in the animal organism. Its half-life time was calculated to be 50 hours. Small amounts were retained in the bones even after 26 days. Oxalic acid is excreted in perceptible amounts in the bile and reaches the intestinal tract. The respiratory CO2 always showed some activity after subcutaneous injection of Cl4-oxalate, whereas no activity was observed after administration to rats with a sterile intestinal tract. It may thus be regarded as proved that the animal organism is not capable of metabolizing oxalic acid. The latter is however oxidized to CO2 by the intest-inal bacteria. Aspergillus niger effects approximately 70% con-version to CO2 of oxalate added to the culture medium.This publication has 3 references indexed in Scilit:
- METABOLISM OF LABELED 2-CARBON ACIDS IN THE INTACT RATJournal of Biological Chemistry, 1951
- THE METABOLISM OF 1-C14-l-ASCORBIC ACID IN GUINEA PIGSJournal of Biological Chemistry, 1951
- Das Verhalten der Oxalsäure bei der Leberdurchströmung1 in vitro (VI. Mitteilung)Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1940