THE ROLE OF ASPERGILLUS-FUMIGATUS ANTIGENS IN BLOOD-COAGULATION AND PLATELET-FUNCTION
- 1 January 1980
- journal article
- research article
- Vol. 28 (112) , 91-96
Abstract
The effects of A. fumigatus antigens on platelet function of rabbits was studied. A. fumigatus antigens produced spontaneous and irreversible aggregation of platelets. Aspirin, indomethacin or lidocaine did not block the antigen-induced aggregation. No aggregations occurred when complement depleted plasma was used. No differences were noted between the strains used. Soluble Aspergillus antigens can cause platelet aggregation in vitro, possibly via a complement dependent pathway. The likely implications of these findings in clinical situations are discussed.This publication has 3 references indexed in Scilit:
- AGGREGATION OF RABBIT PLATELETS BY PLATELET-ACTIVATING FACTOR IS INDEPENDENT OF THE RELEASE REACTION AND THE ARACHIDONATE PATHWAY AND INHIBITED BY MEMBRANE-ACTIVE DRUGS1979
- Pulmonary candidiasis. A clinical and pathological correlationArchives of internal medicine (1960), 1978
- ANTIGENIC VARIABILITY OF ASPERGILLUS-FUMIGATUS STRAINS1977