Tolerance of axenically cultured Entamoeba histolytica and Giardia lamblia to a variety of antimicrobial agents
- 1 January 1985
- journal article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 79 (1) , 60-62
- https://doi.org/10.1016/0035-9203(85)90236-6
Abstract
Twelve antimicrobial agents were tested for use in axenic cultures of Entamoeba histolytica and Giardia lamblia. Ten did not inhibit parasite growth at concentrations of at least two-fold above the effective antibacterial or antifungal levels. We have found the combination of piperacillin (500 μg/ml) plus amikacin (125 (μ/ml) to be useful in (i) axenization of a new strain of E. histolytica, (ii) eradication of multiply drug-resistant contaminants in cultures and (iii) prevention of bacterial growth in experiments with non-sterile components.Keywords
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