THE INFLUENCE OF ADRENALIN ON PLASMA PROTHROMBIN

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Abstract
The effects on plasma prothrombin of different doses of adrenalin intravenously administered into dogs have been studied in normalcy and after production of hypoprothrombinemia by dicumarol. In albino rats, the effects on plasma prothrombin of different doses of adrenalin administered intraven., intramusc, and subcut. have been studied without the production of hypoprothrombinemia by dicumarol. It is concluded that in dogs and in albino rats, the different doses of adrenalin employed produce no significant changes in prothrombin time of dilute plasma in normalcy; and that in dogs, made hypoprothrombinemic by dicumarol, the effects of adrenalin are variable and inconsistent and therefore probably insignificant.

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