Bartter's Syndrome: Contrasting Patterns of Prostaglandin Excretion in Children and Adults
- 1 January 1978
- journal article
- research article
- Published by Portland Press Ltd. in Clinical Science
- Vol. 54 (1) , 115-118
- https://doi.org/10.1042/cs0540115
Abstract
1. The daily urine excretion has been studied of prostaglandins (PG) E2 and F2α, as measured by radioimmunoassay, in eight children and seven adults with Bartter's syndrome. 2. Excretion of both PGE2 and PGF2α was significantly higher in the patients with Bartter's syndrome than in 17 normal children. 3. Twelve normal adults excreted significantly more PGE2 and PGF2α than did the normal children. In contrast, adults with Bartter's syndrome did not show an increase in prostaglandin excretion.Keywords
This publication has 3 references indexed in Scilit:
- Stimulation of renin release from rabbit renal cortex by arachidonic acid and prostaglandin endoperoxides.Circulation Research, 1976
- Bartter's syndrome: A disorder characterized by high urinary prostaglandins and a dependence of hyperreninemia on prostaglandin synthesisThe American Journal of Medicine, 1976
- Hypokalaemic alkalosis and hyperplasia of the juxtaglomerular apparatus without hypertension or oedema.BMJ, 1967