Characterization of conserved properties of hemagglutinin of H5N1 and human influenza viruses: possible consequences for therapy and infection control
Open Access
- 1 January 2009
- journal article
- Published by Springer Nature in BMC Structural Biology
- Vol. 9 (1) , 21
- https://doi.org/10.1186/1472-6807-9-21
Abstract
Epidemics caused by highly pathogenic avian influenza virus (HPAIV) are a continuing threat to human health and to the world's economy. The development of approaches, which help to understand the significance of structural changes resulting from the alarming mutational propensity for human-to-human transmission of HPAIV, is of particularly interest. Here we compare informational and structural properties of the hemagglutinin (HA) of H5N1 virus and human influenza virus subtypes, which are important for the receptor/virus interaction.Keywords
This publication has 23 references indexed in Scilit:
- Application Of The EIIP/ISM Bioinformatics Concept in Development of New DrugsCurrent Medicinal Chemistry, 2007
- MOLECULAR MAKEUP OF HIV-1 ENVELOPE PROTEINInternational Reviews of Immunology, 2004
- Early Alterations of the Receptor-Binding Properties of H1, H2, and H3 Avian Influenza Virus Hemagglutinins after Their Introduction into MammalsJournal of Virology, 2000
- Influenza virus infection of desialylated cellsGlycobiology, 2000
- Receptor Specificity in Human, Avian, and Equine H2 and H3 Influenza Virus IsolatesVirology, 1994
- Influenza virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium; the role of the host cell in selection of hemagglutinin receptor specificityVirus Research, 1993
- Kinetics of protein-protein association explained by Brownian dynamics computer simulation.Proceedings of the National Academy of Sciences, 1992
- Receptor binding properties of human and animal H1 influenza virus isolatesVirology, 1989
- Identification of nanopeptide from HTLV-III, ARV-2 and LAVBRU envelope gp120 determining binding to T4 cell surface protein.1988
- THEORETICAL PREDICTION OF MUTAGENICITY AND CARCINOGENICITY OF CHEMICAL SUBSTANCES1976