The Complications of Diabetes Mellitus

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Abstract
The common perception of the complications of diabetes mellitus has been distorted by the heated controversy over two mutually exclusive unifying theories of their pathogenesis. The complications are a very heterogeneous group of clinical syndromes that are associated with both ketosis-prone juvenile diabetes and maturity-onset diabetes; they include myocardial infarction, uremia, visual impairment resulting from proliferative retinopathy and polyneuropathy. (In populations in which myocardial infarction is uncommon its association with diabetes is not demonstrable.) At present the development of any of these syndromes in any given diabetic patient is quite unpredictable, and there are numerous series of 20-year to 40-year . . .

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