INHIBITION OF YEAST HEXOKINASE BY HOMOLOGOUS ANTISERUM

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Abstract
Antiserum against yeast hexokinase has been produced in the rabbit. This serum, added to the reaction system at the beginning or after the reaction has progressed for 20 min., inhibits the activity of the enzyme. Under optimal conditions the inhibitory effect of the antiserum is immediate. Yeast hexokinase antiserum had no effect on the activity of rat brain hexokinase, nor did a rabbit antihyaluronidase serum show an inhibitory effect on yeast hexokinase. These facts show a high degree of specificity of the inhibitory action of the antiserum obtained.
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