Adult Stem Cells for Tissue Repair — A New Therapeutic Concept?
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- 7 August 2003
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 349 (6) , 570-582
- https://doi.org/10.1056/nejmra022361
Abstract
Adult human stem cells that are intrinsic to various tissues have been described and characterized, some only recently. Analysis of recent data suggests that adult stem cells can generate differentiated cells beyond their own tissue boundaries, a process termed “developmental stem-cell plasticity.” This review focuses on in vivo models of adult stem cells derived from bone marrow and peripheral blood and their potentially novel therapeutic applications.Keywords
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