Role of Langerhans cells in the infection of the guinea-pig epidermis with foot-and-mouth disease virus
- 1 September 1985
- journal article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 83 (3-4) , 331-336
- https://doi.org/10.1007/bf01309929
Abstract
In guinea-pig infected with foot-and-mouth disease virus (FMDV), Langerhans cells in the foot pads increase in number and show viral antigens 24 hours post-inoculation, preceding appearance of virus in epithelial cells and vesiculation. This observation suggests that Langerhans cells may be engaged in virus transport from the blood to the non vascularized epidermis.Keywords
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