CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. XIX. A NOTE ON THE USE OF FIBRINOGEN AND THROMBIN IN THE SURFACE TREATMENT OF BURNS 123

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Abstract
Observations of surgically denuded areas of animals and burns on humans are presented which suggest that human fibrinogen and thrombin mixtures have no deleterious effect on normal processes of repair. The use of preformed fibrin films, prepared from the proteins involved in the natural coagulation mechanism, is described in a small series of 2d and 3d degree burns. Such films are capable of adaptation to many programs of surface therapy. It is suggested that such films, particularly in the form of roll bandages, might prove a highly expedient fibrinogen-thrombin dressing for burns in the field, owing to simplicity and speed from the standpoint of application, and to lack of bulk from the standpoint of transportation.