Saccharomyces cerevisiae acquires resistance to 2-deoxyglucose at a very high frequency
- 1 June 1988
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 170 (6) , 2870-2872
- https://doi.org/10.1128/jb.170.6.2870-2872.1988
Abstract
We have found that Saccharomyces cerevisiae acquires spontaneously increasing resistance to 2-deoxyglucose at a very high frequency. This finding allows the easy isolation of different types of resistant strains of interest for metabolic studies with 2-deoxyhexoses. On the other hand, it sounds a note of caution in the widespread use of 2-deoxyglucose as a selective agent for the isolation of yeast mutants with impaired hexose transport or phosphorylation systems.This publication has 16 references indexed in Scilit:
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