EFFECT OF TOPICAL PILOCARPINE ON INTRAOCULAR-PRESSURE AND PUPIL SIZE IN NORMOTENSIVE AND GLAUCOMATOUS BEAGLE

  • 1 January 1977
    • journal article
    • research article
    • Vol. 16  (12) , 1143-1148
Abstract
Topical 1, 2 and 4% pilocarpine were evaluated in the normotensive and glaucomatous beagles, comparing intraocular pressure (IOP), pupillary size and time. In normotensive beagles pilocarpine produced maximal decreases of 25% (5.5 mm Hg) at 1% concentration, 34% (7.26 mm Hg) at 2% concentration and 25% (6.9 mm Hg) at concentration. The maximum reductions in IOP after pilocarpine instillation in the glaucomatous beagle were 30% (9.1 mm Hg) at 1% concentration, 44% (14.92 mm Hg) at 2% concentration and 31% (10.89 mm Hg) at 4% concentration. The glaucomatous beagles responded with a greater reduction of IOP than did the normotensive beagles.

This publication has 2 references indexed in Scilit: