Tuberculin Conversion Following BCG Vaccination in Preterm Infants

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Abstract
Tuberculin conversion following BCG vaccination was evaluated in 3 groups of infants. Group 1 consisted of 12 preterm appropriate-for-gestational-age (AGA) infants given BCG vaccination at birth; group 2 was made up of 15 term AGA infants similarly immunized while 8 preterm AGA infants (group 3) received BCG about the time estimated to be their normal birth-date. The tuberculin conversion rates of 83%, 93% and 88% in groups 1, 2 and 3, respectively, were not significantly different (P > 0.5). The preterm AGA infants born at 32-36 wk of gestation can apparently be effectively immunized with BCG at birth.