Zinc-Catalyzed Reduction of Amides: Unprecedented Selectivity and Functional Group Tolerance
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- 27 January 2010
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 132 (6) , 1770-1771
- https://doi.org/10.1021/ja910083q
Abstract
A novel zinc-catalyzed reduction of tertiary amides was developed. This system shows remarkable chemoselectivity and substrate scope tolerating ester, ether, nitro, cyano, azo, and keto substituents.Keywords
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