Amoxycillin/clavulanic acid (augmentin)-induced intrahepatic cholestasis
- 1 August 1989
- journal article
- case report
- Published by Springer Nature in Digestive Diseases and Sciences
- Vol. 34 (8) , 1290-1293
- https://doi.org/10.1007/bf01537281
Abstract
Summary A 75-year-old man developed a biopsy-proven, drug-induced intrahepatic cholestasis after use of amoxycillin trihydrate combined with the Β-lactam inhibitor potassium clavulanate (Augmentin). Cholestatic liver injury is an uncommonly recognized, probably immunologically based adverse reaction to therapy with penicillin and its derivatives.Keywords
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