Retrospective Analysis of Predictive Factors for Recurrence After Curatively Resected Papillary Thyroid Carcinoma

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Abstract
This retrospective study analyzes the predictive factors after curative surgery for papillary thyroid carcinoma (PTC). We analyzed 386 patients who underwent a curative operation for PTC in our hospital between 1977 and 1997, subject to the inclusion criteria. According to univariate analysis, pathological lateral cervical lymph node involvement (P < 0.0001), dedifferentiation of the tumor (P < 0.002), male sex (P < 0.0001), a large tumor (P < 0.005), and an age of over 50 years (P < 0.05) were significant factors. Cox’s proportional hazard model showed that a man (P < 0.05), aged over 50 years (P < 0.05), who had a large primary tumor (P < 0.05) with dedifferentiation (P < 0.05), and pathological lateral cervical lymph node metastasis (P < 0.005) was more likely to have recurrence of PTC. Determining whether lymph node metastasis exists could be useful for predicting recurrence in patients who have undergone curative resection of PTC.