COUNTERIMMUNOELECTROPHORESIS IN THE DIAGNOSIS OF HUMAN LEPTOSPIROSIS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 244  (2-3) , 285-290
Abstract
Counterimmunoelectrophoresis (CIE) was applied on sera from patients with leptospirosis caused by leptospires from different serogroups and on sera from a control group. The CIE using an antigen prepared from a single leptospira strain agreed with the microscopic agglutination test using a battery of different antigens in 91% of the leptospirosis sera. CIE was sensitive and specific, comparatively easy to perform, used small amounts of serum and antigen, gave rapid results and allowed the examination of large numbers of specimens at a time.