Thrombomodulin levels in Behçet's disease with and without the factor V Leiden mutation
- 1 May 1998
- journal article
- research article
- Published by Springer Nature in Clinical Rheumatology
- Vol. 17 (3) , 186-188
- https://doi.org/10.1007/bf01451044
Abstract
The plasma levels of thrombomodulin (TM) in 34 patients with Behçet's disease and 79 healthy control subjects were studied. Eight patients had the factor V Leiden (FVL) mutation. The TM level was significantly lower in patients with the FVL mutation than in patients without the mutation and in the healthy controls (pp<0.01). However, there was no difference in overall mean plasma TM concentration between the patients without the mutation and the healthy controls.Keywords
This publication has 9 references indexed in Scilit:
- Elevated levels of soluble thrombomodulin in plasma from children with Arg 506 to Gln mutation in the factor V geneEuropean Journal of Haematology, 2009
- Factor V Q 506 mutation in children with thrombosisAmerican Journal of Hematology, 1996
- Circulating Thrombomodulin as a Clue of Endothelial Damage in Behçet’s DiseaseThrombosis and Haemostasis, 1996
- COAGULATION FACTOR V GENE MUTATION INCREASES THE RISK OF VENOUS THROMBOSIS IN BEHÇET'S DISEASERheumatology, 1995
- Mutation in blood coagulation factor V associated with resistance to activated protein CNature, 1994
- Resistance to Activated Protein C as a Basis for Venous ThrombosisNew England Journal of Medicine, 1994
- C 09 Low levels of circulating thrombomodulin in patients with Behçet's diseaseLa Revue de Médecine Interne, 1993
- Structure and function of thrombomodulin: a natural anticoagulantBlood, 1990