Comparative changes of levels of nitrendipine Ca2+ channels, of tetrodotoxin‐sensitive Na+ channels and of ouabain‐sensitive (Na+ + K+)‐ATPase following denervation of rat and chick skeletal muscle

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Abstract
Three major ion transport systems, the nitrendipine-sensitive Ca2+ channels, the tetrodotoxin-sensitive Na+ channel and the ouabain-sensitive (Na+ + K+-ATPase, have been studied in skeletal muscle from rat and chick after chronic denervation. It is shown that the situation found for the Ca2+ channel differs dramatically from that found for the Na2+ channel and the (Na2+ + K+)-ATPase and that regulation of the nitrendipine-sensitive Ca2+ channel in denervated muscle also differs widely from that of the tetrodotoxinsensitive Na+ channel and the ouabain-sensitive (Na+ + K+-ATPase which show a quite similar evolution.