Selective Inhibition of Herpesvirus Deoxyribonucleic Acid Synthesis by Acycloguanosine, 2′-Fluoro-5-Iodo-Aracytosine, and ( E )-5-(2-Bromovinyl)-2′-Deoxyuridine
Open Access
- 1 May 1981
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 19 (5) , 927-929
- https://doi.org/10.1128/aac.19.5.927
Abstract
The selectivity of inhibition of herpesvirus deoxyribonucleic acid synthesis by acycloguanosine, 2′-fluoro-5-iodo-aracytosine, and ( E )-5-(2-bromovinyl)-2′-deoxyuridine was determined by isopycnic banding of 32 P-labeled deoxyribonucleic acid from herpesvirus-infected and uninfected cells.This publication has 11 references indexed in Scilit:
- 2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agentAntimicrobial Agents and Chemotherapy, 1980
- Enzymatic Targets in Virus ChemotherapyPublished by S. Karger AG ,1979
- Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphateJournal of Virology, 1979
- (E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.Proceedings of the National Academy of Sciences, 1979
- Characteristics of Herpesvirus Mutants Resistant to Phosphonoformate and PhosphonoacetateAntimicrobial Agents and Chemotherapy, 1979
- Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosidesJournal of Medicinal Chemistry, 1979
- 9-(2-Hydroxyethoxymethyl)guanine activity against viruses of the herpes groupNature, 1978
- Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanineProceedings of the National Academy of Sciences, 1977
- THE SELECTIVE INHIBITION OF VIRAL DNA SYNTHESIS BY CHEMOTHERAPEUTIC AGENTS: AN INDICATOR OF CLINICAL USEFULNESS? *Annals of the New York Academy of Sciences, 1977
- Nucleoside analogs with antiviral activityBiochemical Pharmacology, 1976