Thyroid-hormone modulation of the number of β-adrenergic receptors in rat fat-cell membranes
- 15 December 1978
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 176 (3) , 1007-1010
- https://doi.org/10.1042/bj1761007
Abstract
Adipocytes from thyroidectomized rats contain 3 times less [3H]dihydroalprenolol-binding sites (.beta.-adrenergic receptors) than adipocytes from euthyroid animals. This alteration is not solely due to cell-size differences, but also to a thyroidectomy-induced defect in .beta.-adrenergic receptor density per adipocyte surface area, a defect that is corrected by triiodothyronine treatment.This publication has 22 references indexed in Scilit:
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