Abstract
The assumption is made that the effect of a meta or para substituent X on the reactivity of a reacting center Y in a compound [Complex chemical formula] depends only on the electron density change induced by the substituent in the atom at which Y is attached to R. Using this assumption relative values of Hammett's reaction constant (ρ) are calculated for a given reaction in several series of compounds having the above formula. The calculations require the computation of the electron density changes induced by substituents in the atom at which Y is attached to R. The computations are carried out by the semiempirical LCAO MO method for several cases where R and the benzene ring form part of a single conjugated system. The resulting relative ρ‐values are compared with experimental data. Reasonable agreement is found.

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