Cloning of the mouse homologue of the yeast cell cycle control gene cdc2
- 1 January 1990
- journal article
- research article
- Published by Taylor & Francis in DNA Sequence
- Vol. 1 (1) , 49-54
- https://doi.org/10.3109/10425179009041346
Abstract
The cdc2 cell cycle control genes of yeast and man encode 34 kOa protein kinases. Using the human CDC2 gene as a ONA probe we have isolated cDNA clones corresponding to the mouse cdc2 gene. Sequencing of the mouse clones show 96% identity at the amino acid level to the human COO gene and detects a 2 kb RNA product indistinguishable to that seen in human cells. The mouse gene should be useful in studying the functional control of the cell cycle in mouse cells.Keywords
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