Effects of Human Menopausal Gonadotropin and Ovine Follicle Stimulating Hormone on Lactic Acid Production by Ovaries from Prepubertal Rats

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Abstract
Two preparations of follicle stimulating hormone extracted from human menopausal urine have been compared with an ovine preparation of FSH in relation to their effects on lactic acid production by ovaries from prepubertal rats. It was found that all 3 preparations stimulated lactic acid production when added in vitro and that the slopes of the dose-response curves did not differ. These results strongly support a previous suggestion that FSH [follicle-stimulating hormone] has effects on the carbohydrate metabolism of the prepubertal rat ovary.