Experiments on the chemotherapy of cancer

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Abstract
An attempt was made to express quantitatively and statistically the effect of substances which inhibit tumor growth. Heptaldehyde given to mice has some inhibitory action on the growth of spontaneous carcinomata and grafted sarcomata. A similar effect is produced by di-carboxylic acids (particularly malonic acid) which are possible metabolic products of heptaldehyde. Citral has more inhibitory action on tumor growth than heptaldehyde but the monocarboxylic and dicarboxylic acids derived from citral have only slight effect.

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