Posaconazole: A new oral antifungal agent with an expanded spectrum of activity
- 1 February 2009
- journal article
- review article
- Published by Oxford University Press (OUP) in American Journal of Health-System Pharmacy
- Vol. 66 (3) , 225-236
- https://doi.org/10.2146/ajhp070532
Abstract
Purpose. The pharmacology, pharmacokinetics, pharmacodynamics, spectrum of activity and resistance, clinical utility, adverse effects, dosage and administration, and recommended monitoring of posaconazole are reviewed.Keywords
This publication has 116 references indexed in Scilit:
- In Vitro Susceptibilities of 217 Clinical Isolates of Zygomycetes to Conventional and New Antifungal AgentsAntimicrobial Agents and Chemotherapy, 2007
- In Vitro Activities of Amphotericin B, Caspofungin, Itraconazole, Posaconazole, and Voriconazole against 45 Clinical Isolates of Zygomycetes: Comparison of CLSI M38-A, Sensititre YeastOne, and the EtestAntimicrobial Agents and Chemotherapy, 2007
- Posaconazole Plasma Concentrations in Juvenile Patients with Invasive Fungal InfectionAntimicrobial Agents and Chemotherapy, 2007
- Antifungal Susceptibilities of the Species of the Pseudallescheria boydii ComplexAntimicrobial Agents and Chemotherapy, 2006
- Molecular Basis for Enhanced Activity of Posaconazole against Absidia corymbifera and Rhizopus oryzaeAntimicrobial Agents and Chemotherapy, 2006
- Interaction between Posaconazole and Caspofungin in Concomitant Treatment of Mice with Systemic Aspergillus InfectionAntimicrobial Agents and Chemotherapy, 2006
- In Vitro Activities of Posaconazole, Fluconazole, Itraconazole, Voriconazole, and Amphotericin B against a Large Collection of Clinically Important Molds and YeastsAntimicrobial Agents and Chemotherapy, 2006
- Pharmacokinetics and Safety of Oral Posaconazole in Neutropenic Stem Cell Transplant RecipientsAntimicrobial Agents and Chemotherapy, 2006
- Effect of a Nutritional Supplement on Posaconazole Pharmacokinetics following Oral Administration to Healthy VolunteersAntimicrobial Agents and Chemotherapy, 2006
- In vitro activities of voriconazole, posaconazole, and fluconazole against 4,169 clinical isolates of Candida spp. and Cryptococcus neoformans collected during 2001 and 2002 in the ARTEMIS global antifungal surveillance programDiagnostic Microbiology and Infectious Disease, 2004