Mechanism of hydrazine excretion by the mammalian kidney
- 31 January 1967
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 212 (2) , 394-399
- https://doi.org/10.1152/ajplegacy.1967.212.2.394
Abstract
Hydrazine excretion by the mamalian kidney involves glomerular filtration, tubular reabsorption, and secretion. It is reduced by elevation of urine pH. Hydrazine reabsorption exhibits the characteristics of a diffusion-mediated process: it is independent of the plasma concentration or the filtered load of hydrazine and is reversibly and linearly decreased by mannitol diuresis. The secretion process has a limited capacity for hydrazine transport and is inhibited by 2, 4-dinitrophenol and, to a small extent, by thiamine.This publication has 6 references indexed in Scilit:
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