Fleroxacin (Ro 23-6240): activity in virtro against 355 enteropathogenic and non-fermentative Gram-negative bacilli and Legionella pneumophila

Abstract
The antibacterial activity of fleroxacin (Ro 23-6240, AM-833), a new 6-fluoroquinolone, was determined against 149 strains of enteropathogenic bacteria (17 species) and 191 strains (28 species) of glucose non-fermentative Gram-negative rods (excluding Pseudomonas aeruginosa), and against 15 strains of Legionella pneumophila. The cumulative susceptibility of these groups of bacteria to Ro 23-6240 at the 2 mg/l level were 99.2% 80.1 and 100% of tested strains, respectively.

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