Crystallographic investigations of the tryptophan‐derived cofactor in the quinoprotein methylamine dehydrogenase
- 5 August 1991
- journal article
- Published by Wiley in FEBS Letters
- Vol. 287 (1-2) , 163-166
- https://doi.org/10.1016/0014-5793(91)80041-z
Abstract
A model of tryptophan tryptophylquinone (TTQ), recently proposed by Mclntire et al. (Science (1991) 252, 817-824) to be the prosthetic group of the quinoprotein methylamine dehydrogenase, has been compared with electron density maps of this dehydrogenase from Thiobacillus versutus and Paracoccus denitrificans . The comparison shows that the TTQ model can be neatly accommodated, providing strong supportive evidence that TTQ is indeed the cofactor for this group of quinoproteins.Keywords
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