Auricular Fibrillation Induced and Maintained in Animals by Acetylcholine or Vagal Stimulation
- 1 July 1955
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 3 (4) , 390-396
- https://doi.org/10.1161/01.res.3.4.390
Abstract
Animals pretreated with appropriate doses of anticholinesterase agents develop auricular flutter and fibrillation following injection of acetylcholine or vagal stimulation. Depression of normal sinoauricular nodal function facilitates induction of fibrillation. During fibrillation, additional injections of acetylcholine, or vagal stimulation, increase the rate of fibrillation. Atropine in small doses reverts the fibrillation to normal sinus rhythm.Keywords
This publication has 7 references indexed in Scilit:
- Observations on Pharmacology of the Anticholinesterases Sarin and TabunExperimental Biology and Medicine, 1954
- EFFECTS OF ACETYLCHOLINE ON MECHANICAL AND ELECTRICAL PROPERTIES OF ISOLATED RABBIT AURICLE - THEIR RELATIONSHIP TO THE GENESIS OF ARRHYTHMIAS1954
- Effect of Diffusion Respiration on Duration of Vagal Cardiac ArrestExperimental Biology and Medicine, 1954
- Action of Aconitine on the Gold-Blooded Heart.Experimental Biology and Medicine, 1953
- Abnormal Cardiac Rhythms Caused by AcetylcholineCirculation, 1951
- ANALYSIS OF THE ACTIONS OF ACETYLCHOLINE, ATROPINE, EPINEPHRINE AND QUINIDINE ON HEART MUSCLE OF THE CAT1951
- Further Studies on Mechanism of Auricular Fibrillation.Experimental Biology and Medicine, 1950