Adrenocortical Function in Chronic Pulmonary Disease

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Abstract
RECENT reviews have emphasized the fact that in patients with pulmonary emphysema, there is an extraordinarily high incidence of peptic ulceration.1 2 3 4 It has further been shown that complications of peptic ulcer are more common in these patients than in those without pulmonary disease. The incidence of peptic ulcer in subjects with chronic obstructive pulmonary disease ranges in different series from 19 to 43 per cent. It has been postulated that patients with chronic obstructive airway disease are in a state of constant stress that induces hyperadrenocorticism, with a resultant high incidence of peptic ulcer. However, definitive studies to substantiate this . . .