EXPERIMENTAL BONE MARROW REACTIONS

Abstract
A study of the effect of feeding kidney, pancreas, brain and spleen on blood and body weight regeneration of pigeons in which partial bone marrow aplasia and anemia had been produced by starvation. Broiled kidney feeding gave variable results, a few animals regaining their weight, red blood cells and hemoglobin, while others were definitely anemic at the end of the period of feeding. Pancreas proved to be adequate while brain was deficient as a food. Spleen caused an excellent regeneration of red blood cells and hemogoblin, while gain in weight was slow. The bone marrows in the pigeons fed kidney showed a variable microscopical picture, in those fed pancreas slightly more erythrocytic hyperplasia than normal, in spleen fed animals less hyperplasia, and in brain fed, aplasia in 2 animals. It is concluded that kidney as an exclusive food is not as effective as pancreas or spleen for blood regeneration in a nutritional anemia caused by starvation, while brain is inadequate.

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