Antibody Production by Nonimmune Spleen Cells Incubated with RNA from Immunized Mice
- 22 May 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 144 (3621) , 1012-1013
- https://doi.org/10.1126/science.144.3621.1012
Abstract
RNA isolated from the spleens of B6AF1 mice immunized to sheep red blood cells was incubated with the spleen cells of nonimmunized mice. The number of antibody-forming cells detected by the Jerne plaque technique was significantly higher among the cells incubated with the RNA from immune animals than among cells incubated without RNA, or with RNA from nonimmune animals.Keywords
This publication has 6 references indexed in Scilit:
- RNA-INDUCED BIOSYNTHESIS OF SPECIFIC ENZYMESProceedings of the National Academy of Sciences, 1962
- Ribonucleic Acid in "Transformation" of Lymphoid CellsScience, 1962
- Sedimentation characteristics of rapidly labelled RNA from HeLa cellsBiochemical and Biophysical Research Communications, 1962
- ANTIBODY FORMATION IN VITROThe Journal of Experimental Medicine, 1961
- Amino Acid Metabolism in Mammalian Cell CulturesScience, 1959
- INFECTIVITY OF RIBONUCLEIC ACID FROM POLIOVIRUS IN HUMAN CELL MONOLAYERSThe Journal of Experimental Medicine, 1958