An Analysis of Autograft Fixation After Anterior Cruciate Ligament Reconstruction in a Rabbit Model

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Abstract
Fixation and incorporation of a tendon implanted within the bone pose theoretical as well as practical concerns for the surgeon who treats instability problems of the knee. Understanding the physiology involved in graft- bone incorporation is necessary for the appropriate re habilitation of patients who undergo anterior cruciate ligament surgery. The purpose of the study was to ex amine the histologic and biomechanical changes of a semitendinosus autograft reconstruction of the anterior cruciate ligament in a rabbit model at the graft-bone tunnel interface in the femur. The results indicate that by 3 weeks, failure of the bone-graft-bone or construction is through the intraarticular portion of the graft, not as a result of pullout from the bone tunnel. Graft fixation of the bone tunnel occurs by an intertwining of graft and connective tissue and anchoring of connective tis sue to bone by collagenous fibers and bone formation in the tunnels. The collagenous fibers have the appear ance of the Sharpey's fibers seen in an indirect tendon insertion.