STUDIES IN HISTOCHEMISTRY: EFFECTS OF STRESS CONDITIONS, ACTH, CORTISONE, DESOXYCORTICOSTERONE AND HYPOPHYSECTOMY ON THE QUANTITATIVE HISTOLOGICAL DISTRIBUTION OF PHENOLSULFATASE AND ACETYLCHOLINESTERASE IN THE RAT ADRENAL12

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Abstract
Treatment of male albino rats with ACTH, DCA, or cortisone, and subjecting them to the stress conditions of turpentine abscess or cold, failed to cause demonstrable changes in the concentration or histological distribution of phenolsulfatase activity based on the protein-nitrogen content. Six days after hypophysectomy a marked decline in the activities in the fascicular and reticular zones was found, and this effect was almost as great as that observed after 30 days. The enzyme was localized primarily in the inner fasciculata and outer reticularis. Acetylcholinesterase was not influenced by hormone treatments and turpentine abscess. Hypophysectomy had minor influences on the magnitude of the activity or distribution of the enzyme. The enzyme was localized primarily in the medulla.