The interaction of presynaptic polarization with calcium and magnesium in modifying spontaneous transmitter release from mammalian motor nerve terminals

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Abstract
1. The relationship between motor terminal polarization and miniature end-plate potential (m.e.p.p.) frequency was examined in the presence of various Ca, Mg and K concentrations ([Ca], [Mg] and [K]) and also at modified bathing osmolarity levels. The polarization changes were obtained with `electrotonic' and `focal' polarizing currents and with rapid changes in bathing [K].