The Amino Acid Sequence of the Double-Headed Proteinase Inhibitor from Canine Submandibular Glands, III. Sequencing studies
- 1 January 1975
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 356 (2) , 1865-1878
- https://doi.org/10.1515/bchm2.1975.356.2.1865
Abstract
Canine submandibular glands contain 3 polyvalent, double-headed proteinase inhibitors. The amino acid sequences of the 2 main inhibitors were determined. They differ only in the substitution of one Lys for a Glu residue. The inhibitor molecules are composed of 2 halves (domains), one antitryptic and one antichymotryptic. The 2 domains are covalently linked by 3 amino acid residues. The domains are structurally related to each other and to the sequenced monovalent secretory pancreatic trypsin inhibitors.This publication has 1 reference indexed in Scilit:
- Die Aminosäuresequenz des doppelköpfigen Proteinaseninhibitors aus der Glandula submandibularis des Hundes, II. Ein Methioninrest als reaktives Hemmzentrum für ChymotrypsinHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1975