Dual effects of microwaves on single Ca2+‐activated K+ channels in cultured kidney cells Vero
- 6 February 1995
- journal article
- Published by Wiley in FEBS Letters
- Vol. 359 (1) , 85-88
- https://doi.org/10.1016/0014-5793(95)00002-q
Abstract
Using the patch voltage-clamp method, possible effects of millimetre microwaves (42.25 GHz) on single Ca(2+)-activated K+ channels in cultured kidney cells (Vero) were investigated. It was found that exposure to the field of non-thermal power (about 100 microW/cm2) for 20-30 min greatly modifies both the Hill coefficient and an apparent affinity of the channels for Ca2+(i). The data suggest that the field alters both cooperativity and binding characteristics of the channel activation by internal Ca2+. The effects depend on initial sensitivity of the channels to Ca2+ and the Ca2+ concentration applied.Keywords
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