Monitoring the production yields of vincristine and vinblastine in Catharanthus roseus from somatic embryogenesis. Semiquantitative determination by flow‐injection electrospray ionization mass spectrometry
- 14 February 2001
- journal article
- research article
- Published by Wiley in Rapid Communications in Mass Spectrometry
- Vol. 15 (5) , 364-369
- https://doi.org/10.1002/rcm.239
Abstract
A semiquantitative determination of two bis-indole antitumor alkaloids, vincristine and vinblastine, has been performed by flow-injection electrospray ionization mass spectrometric analysis of the extracts of Catharanthus roseus. Leaves and flowers of two different phenotypes (pink flower and white flower) obtained from somatic embryogenesis were thus examined and compared with the field-grown mother plant. Different amounts of vincristine and vinblastine were detected depending on the examined samples. Copyright © 2001 John Wiley & Sons, Ltd.Keywords
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