Persisting Exo-erythrocytic Cycle in Plasmodium Cynomolgi
- 26 June 1948
- Vol. 1 (4564) , 1225-1228
- https://doi.org/10.1136/bmj.1.4564.1225
Abstract
A monkey (Macaca mulatta) infected with P. cynomolgi developed a characteristic malarial infection, with parasites in the blood for about 2 months. Two months after parasites had disappeared from the blood a liver biopsy revealed 2 bodies, one 16u and the other 30u in diam., which were considered to be exo-erythrocytic forms of P cynomolgi. Shortly after the operation parasites again appeared in the blood. The authors consider that relapses in patients treated for malaria result from the persistence of the exo-erythrocytic stage of the organism in the liver.Keywords
This publication has 2 references indexed in Scilit:
- The pre-erythrocytic development of Plasmodium cynomolgi and Plasmodium viv axTransactions of the Royal Society of Tropical Medicine and Hygiene, 1948
- CHEMOTHERAPEUTIC SUPPRESSION AND PROPHYLAXIS IN MALARIA - AN EXPERIMENTAL INVESTIGATION UNDERTAKEN BY MEDICAL RESEARCH TEAMS] IN AUSTRALIA1945