Abstract
The reaction rates and immunogenicity of primary immunization with tetanus (5 flocculation [Lf] units) and diphtheria (1.5 Lf units) toxoids were evaluated in older children and adults. Eight of 42 subjects had local reactions to .gtoreq. 1 doses of vaccine. All subjects had protective titers to tetanus and 94% to diphtheria after 2 injections. Titers of antitoxins were greater in younger patients; in those younger than 19 yr, they were inversely related to age.