ZINC IN HUMAN BLOOD CELLS: NORMAL VALUES AND ABNORMALITIES ASSOCIATED WITH LIVER DISEASE*
Open Access
- 1 November 1960
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 39 (11) , 1651-1656
- https://doi.org/10.1172/jci104188
Abstract
Mean values for normal persons with an acid extraction - dithizone method are 12.1 (SD[plus or minus]1.51) ug Zn/1010 red cells and 103 (SD[plus or minus]25.5) ug Zn/1010 white cells. The presence of low serum Zn levels in patients with cirrhosis is confirmed, and decreased intracellular Zn is established by the finding of 72.9 (SD[plus or minus]19.9) ug Zn/1010 white cells in a group of 15 cirrhotics. The level of Zn in red cells seems to vary with their mean corpuscular volume.Keywords
This publication has 13 references indexed in Scilit:
- THE ZINC CONTENT OF PLASMA AND ERYTHROCYTES OF PATIENTS WITH PERNICIOUS ANEMIA, SICKLE CELL ANEMIA, POLYCYTHEMIA VERA, LEUKEMIA, AND NEOPLASTIC DISEASE1960
- Biochemistry, Physiology and Pathology of ZincPhysiological Reviews, 1959
- [Zinc metabolism in liver cirrhosis].1958
- Zinc Metabolism in Hepatic DysfunctionNew England Journal of Medicine, 1957
- Zinc Metabolism in Hepatic DysfunctionNew England Journal of Medicine, 1956
- Untersuchungen zur Pathophysiologie des ZinkstoffwechselsJournal of Molecular Medicine, 1956
- Determination of Zinc in Biological MaterialsPublished by Wiley ,1956
- [Petechial test with the vaso-test apparatus].1954
- *UNTERSUCHUNGEN UBER DIE BESTIMMUNG VON ZINK MIT DITHIZON IN BIOLOGISCHEN PRAPARATEN1954
- PRECIPITATION BY TRICHLOROACETIC ACID AS A SIMPLIFICATION IN THE DETERMINATION OF ZINC IN BLOOD AND ITS COMPONENTSJournal of Biological Chemistry, 1949