Influence of Solid Friction on Polymer Relaxation in Gel Electrophoresis
- 18 June 1993
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 260 (5115) , 1782-1784
- https://doi.org/10.1126/science.260.5115.1782
Abstract
Solid friction between a charged polymer and fixed gel points can dramatically affect polymer mobility in gel electrophoresis. The effect is present when a polymer chain is entangled over many gel points along a portion of its length, leading to significantly different behavior than predicted by conventional theory: the mobility of the chain decreases and exhibits a stronger length dependence, which separates long linear charged polymers of different molecular weights.Keywords
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