Amino-terminal sequence analysis of the structural proteins of Sindbis virus.
- 1 June 1978
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 75 (6) , 2722-2726
- https://doi.org/10.1073/pnas.75.6.2722
Abstract
The structural proteins of Sindbis virus, an enveloped virus which belongs to the Togavirus family, were subjected to automated Edman degradation using improved techniques. Extensive NH2-terminal sequences of about 50 residues were determined for each of the 2 membrane glycoproteins. In both cases the NH2 terminus of the molecule was similar in composition to typical water-soluble proteins. The viral capsid protein had a blocked .alpha.-amino group. This is consistent with other observations that viral proteins derived from the NH2 terminus of precursor molecules are often blocked.This publication has 23 references indexed in Scilit:
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