Immunosuppression by whole-body irradiation and its effect on oedema in experimental cerebral ischaemia
- 1 September 1992
- journal article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 86 (3) , 256-259
- https://doi.org/10.1111/j.1600-0404.1992.tb05081.x
Abstract
The effect of global immunosuppression by sublethal whole body X-irradiation on the development of cerebral oedema was assessed 24 h after right middle cerebral artery occlusion in the rat. Irradiation produced a significant leukopenia and thrombocytopaenia, and significantly reduced cortical oedema when compared to non-irradiated control animals.Keywords
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