Comparative acidic cleavage experiments with methyl-substituted benzyl esters of amino acids
- 1 January 1967
- journal article
- research article
- Published by CSIRO Publishing in Australian Journal of Chemistry
- Vol. 20 (10) , 2243-+
- https://doi.org/10.1071/ch9672243
Abstract
The action of trifluoroacetic acid and hydrogen bromide in acetic acid, respectively, on the benzyl, p-methylbenzyl, 2,4,6-trimethylbenzyl, and penta-methylbenzyl esters of some amino acid derivatives has been investigated by thin-layer chromatography. Methyl substitution greatly enhances the lability of the ester groups. The possible bearing of the results on solid-phase peptide synthesis is discussed.Keywords
This publication has 4 references indexed in Scilit:
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