Seminal pepsinogen C is not identical with, but is very similar to gastric pepsinogen C
- 26 September 1988
- journal article
- Published by Wiley in FEBS Letters
- Vol. 238 (1) , 101-104
- https://doi.org/10.1016/0014-5793(88)80234-5
Abstract
Human seminal pepsinogen C has been purified and compared with gastric pepsinogen C. The two zymogens cannot be distinguished by amino acid compositions and sequences of the first 28 N‐terminal amino acid residues are identical. Apparent immunological identity is observed with polyclonal antisera. Monoclonal antibodies toward seminal pepsinogen C have been produced. One is able to recognize a non‐carbohydrate antigenic determinant only present in seminal pepsinogen C.Keywords
This publication has 11 references indexed in Scilit:
- Primary structure of human pepsinogen C gene.Journal of Biological Chemistry, 1988
- Demonstration of pepsinogen C in human pancreatic islets.Gut, 1987
- Evolution in the structure and function of aspartic proteasesJournal of Cellular Biochemistry, 1987
- Gossypol prevents activation of purified proenzyme of human seminal plasma acidic proteinaseBiochimica et Biophysica Acta (BBA) - General Subjects, 1986
- Methods for detection of proteinases: electrophoretic and immunological comparison of aspartic proteinases of different originsPublished by Walter de Gruyter GmbH ,1985
- Assay for the specificity of monoclonal antibodies in crossed immunoelectrophoresisJournal of Immunological Methods, 1984
- Human ProgastricsinEuropean Journal of Biochemistry, 1982
- Theory and methods for immunization in culture and monoclonal antibody productionJournal of Immunological Methods, 1982
- Activation of proenzyme of acidic protease from human seminal plasmaBiochimica et Biophysica Acta (BBA) - Enzymology, 1976
- Pepsinogen in Human Seminal FluidNature, 1952