Modification of DNA with potent mutacarcinogenic 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole isolated from a glutamic acid pyrolysate: structure of the modified nucleic acid base and initial chemical event caused by the mutagen

This publication has 12 references indexed in Scilit:

• Interaction of mutagens isolated from L-glutamic acid pyrolysate with DNA
  Biochemical and Biophysical Research Communications, 1980
• Non-covalent interaction with DNA of the mutagens 2-amino-dipyrido[1,2-a:3′,2′-d]imidazole and methyl-substituted isomers
  Biochemical and Biophysical Research Communications, 1980
• Activation of a mutagen, 3-amino-1-methyl-5H-pyrido[4,3-b]indole. Identification of 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole and its reaction with DNA
  Biochemical and Biophysical Research Communications, 1980
• Detection of potent mutagens, Trp-P-1 and Trp-P-2, in broiled fish
  Cancer Letters, 1980
• In vitro reaction of the carcinogen, N-hydroxy-2-naphthylamine, with DNA at the C-8 and N² atoms of guanine and at the N⁶ atom of adenine
  Carcinogenesis: Integrative Cancer Research, 1980
• Metabolic activation of a mutagen, 2-amino-6-methyldipyrido-[1,2-a:3′,2′-d]imidazole. Identification of 2-hydroxyamino-6-methyldipyrido[1,2-a:3′,2′-d]imidazole and its reaction with DNA
  Biochemical and Biophysical Research Communications, 1980
• Structural identification of a modified base in DNA covalently bound with mutagenic 3-amino-1-methyl-5H-pyrido[4,3-b]indole.
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1979
• Rat liver microsome-mediated binding to DNA of 3-amino-1-methyl-5H-pyrido[4,3-b]indole, a potent mutagen isolated from tryptophan pyrolysate.
  Chemico-Biological Interactions, 1978
• Isolation and structure studies of mutagenic principles in amino acid pyrolysates.
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1978
• Synthesis of a mutagenic principle isolated from tryptophan pyrolysate.
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1977